Search Results
Author: Van Hulle, Carol A.
Resulting in 25 citations.
| 1. |
D'Onofrio, Brian M. Donahue, Kelly L Coyne, Claire A. Van Hulle, Carol A. Rodgers, Joseph Lee Waldman, Irwin D. Lahey, Benjamin B. |
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Early Maternal Age at Childbearing and Offspring Functioning During Adolescence: A Sibling-Comparison Study of Sexual Behavior and Depression Presented: Minneapolis MN, Behavior Genetics Association Annual Meeting, 2009 Cohort(s): Children of the NLSY79, NLSY79 Young Adult Publisher: Behavior Genetics Association Keyword(s): Age at Birth; Age at First Intercourse; CESD (Depression Scale); Depression (see also CESD); Sexual Activity; Siblings Permission to reprint the abstract has not been received from the publisher. Offspring born to younger mothers are at increased risk for problems during adolescence across a range of domains. Previous research suggests that the mechanisms responsible for the associations between offspring adjustment and early maternal age at childbearing (MAC) are dependent on the outcomes being explored. The current study used statistical covariates and the comparison of siblings differentially exposed to MAC to account for alternative explanations for the statistical relations with risky sexual behavior and depression during adolescence. The study included 6,056 offspring (ages 14–21) born to a nationally representative sample of women in the US from the National Longitudinal Survey of Youth and children of the NLSY studies. MAC in the sample ranged from 13- to 34-year-old (M = 23.2). Each increasing year of maternal childbearing was associated with a 14% reduction (OR = 0.86, p\0.001) in the risk of early sexual intercourse (before the age of 14). For instance, offspring born to teenage mothers were 2.46 times more likely to have sex before the age of 14 than offspring born to non-teenage mothers. The association between MAC and early sexual activity remained when controlling for maternal characteristics, such as race/ethnicity, adolescent delinquency, depression, and educational level, and when comparing differentially exposed siblings (OR = .93, p\0.05). Maternal teenage childbearing was also associated with offspring adolescent depression (from ages 14- to 17-year-old), as measured by the CESD (b = -0.04 SD/year at childbearing, p\0.001). The association remained when controlling for maternal covariates and when comparing siblings differentially exposed (b = -0.04 SD/year at childbearing, p\0.001). The results suggest that environmental factors specifically associated with early childbearing account for increased risk of early sexual activity and adolescent depression in offspring. |
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Bibliography Citation
D'Onofrio, Brian M., Kelly L Donahue, Claire A. Coyne, Carol A. Van Hulle, Joseph Lee Rodgers, Irwin D. Waldman and Benjamin B. Lahey. "Early Maternal Age at Childbearing and Offspring Functioning During Adolescence: A Sibling-Comparison Study of Sexual Behavior and Depression." Presented: Minneapolis MN, Behavior Genetics Association Annual Meeting, 2009. |
| 2. |
D'Onofrio, Brian M. Goodnight, Jackson A. Van Hulle, Carol A. Rodgers, Joseph Lee Rathouz, Paul J. Waldman, Irwin D. Lahey, Benjamin B. |
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A Quasi-Experimental Analysis of the Association Between Family Income and Offspring Conduct Problems Journal of Abnormal Child Psychology 37,3 (April 2009):415–429. Also: http://www.springerlink.com/content/c84v1067388u5786/ Cohort(s): Children of the NLSY79, NLSY79 Publisher: Springer Keyword(s): Age at First Birth; Armed Services Vocational Aptitude Battery (ASVAB); Behavior Problems Index (BPI); Behavior, Antisocial; Birth Order; Family Characteristics; Family Income; Gender Differences; Kinship; Modeling, Multilevel; Mothers, Behavior; Siblings; Variables, Independent - Covariate Permission to reprint the abstract has not been received from the publisher. The study presents a quasi-experimental analysis of data on 9,194 offspring (ages 4–11 years old) of women from a nationally representative U.S. sample of households to test the causal hypotheses about the association between family income and childhood conduct problems (CPs). Comparison of unrelated individuals in the sample indicated a robust inverse association, with the relation being larger at higher levels of income and for male offspring, even when statistical covariates were included to account for measured confounds that distinguish different families. Offspring also were compared to their siblings and cousins who were exposed to different levels of family income in childhood to rule out unmeasured environmental and genetic factors confounded with family income as explanations for the association. In these within-family analyses, boys exposed to lower family income still exhibited significantly higher levels of CPs. When considered in the context of previous studies using different designs, these results support the inference that family income influences CPs, particularly in males, through causal environmental processes specifically related to earnings within the nuclear family. |
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Bibliography Citation
D'Onofrio, Brian M., Jackson A. Goodnight, Carol A. Van Hulle, Joseph Lee Rodgers, Paul J. Rathouz, Irwin D. Waldman and Benjamin B. Lahey. "A Quasi-Experimental Analysis of the Association Between Family Income and Offspring Conduct Problems." Journal of Abnormal Child Psychology 37,3 (April 2009):415–429. A.
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| 3. |
D'Onofrio, Brian M. Goodnight, Jackson A. Van Hulle, Carol A. Rodgers, Joseph Lee Rathouz, Paul J. Waldman, Irwin D. Lahey, Benjamin B. |
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Maternal Age at Childbirth and Offspring Disruptive Behaviors: Testing the Causal Hypothesis Journal of Child Psychology and Psychiatry 50,8 (August 2009): 1018-1028. Also: http://onlinelibrary.wiley.com/doi/10.1111/j.1469-7610.2009.02068.x/full Cohort(s): Children of the NLSY79 Publisher: Blackwell Publishing, Inc. => Wiley Online Keyword(s): Age at Birth; Behavior Problems Index (BPI); Child Self-Administered Supplement (CSAS); Children, Behavioral Development; Delinquency/Gang Activity; Siblings Recent studies suggest that the association between Background: maternal age at childbearing (MAC) and children's disruptive behaviors is the result of family factors that are confounded with both variables, rather than a casual effect of environmental factors specifically related to MAC. These studies, however, relied on restricted samples and did not use the strongest approach to test causal influences. Using data on 9,171 4–9-year-old and 6,592 10–13-year-old Methods: offspring of women from a nationally representative sample of US households, we conducted sibling-comparison analyses. The analyses ruled out all genetic factors that could confound the association, as well as all environmental confounds that differ between unrelated nuclear families, providing a strong test of the causal hypothesis that the environments of children born at different maternal ages influence mother- and self-reported disruptive behaviors. When these genetic and environmental confounds were ruled out Results: as alternative explanations, the relation between environments within nuclear families specifically associated with MAC and disruptive behaviors was robust, with the association being stronger for second- and third-born children. Environmental factors specifically associated with early Conclusions: MAC within nuclear families account for increased risk of offspring disruptive behaviors, especially in later-born children. |
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Bibliography Citation
D'Onofrio, Brian M., Jackson A. Goodnight, Carol A. Van Hulle, Joseph Lee Rodgers, Paul J. Rathouz, Irwin D. Waldman and Benjamin B. Lahey. "Maternal Age at Childbirth and Offspring Disruptive Behaviors: Testing the Causal Hypothesis." Journal of Child Psychology and Psychiatry 50,8 (August 2009): 1018-1028.
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| 4. |
D'Onofrio, Brian M. Rickert, Martin E. Langström, Niklas Donahue, Kelly L Coyne, Claire A. Larsson, Henrik Ellingson, Jarrod M. Van Hulle, Carol A. Iliadou, Anastasia N. Rathouz, Paul J. Lahey, Benjamin B. Lichtenstein, Paul |
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Familial Confounding of the Association Between Maternal Smoking During Pregnancy and Offspring Substance Use and Problems Archives of General Psychiatry 69,11 (November 2012): 1140-1150. Also: http://archpsyc.jamanetwork.com/article.aspx?articleid=1389367 Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult Publisher: American Medical Association Keyword(s): Adolescent Behavior; Alcohol Use; Birth Order; Child Self-Administered Supplement (CSAS); Cigarette Use (see Smoking); Intergenerational Patterns/Transmission; Mothers, Behavior; Mothers, Health; Pre/post Natal Behavior; Siblings; Smoking (see Cigarette Use); Substance Use; Sweden, Swedish Permission to reprint the abstract has not been received from the publisher. Objective: To determine the extent to which the association between SDP and offspring substance use/problems depends on confounded familial background factors by using a quasi-experimental design. Design: We used 2 separate samples from the United States and Sweden. The analyses prospectively predicted multiple indices of substance use and problems while controlling for statistical covariates and comparing differentially exposed siblings to minimize confounding. Conclusions: The association between maternal SDP and offspring substance use/problems is likely due to familial background factors, not a causal influence, because siblings have similar rates of substance use and problems regardless of their specific exposure to SDP. |
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Bibliography Citation
D'Onofrio, Brian M., Martin E. Rickert, Niklas Langström, Kelly L Donahue, Claire A. Coyne, Henrik Larsson, Jarrod M. Ellingson, Carol A. Van Hulle, Anastasia N. Iliadou, Paul J. Rathouz, Benjamin B. Lahey and Paul Lichtenstein. "Familial Confounding of the Association Between Maternal Smoking During Pregnancy and Offspring Substance Use and Problems." Archives of General Psychiatry 69,11 (November 2012): 1140-1150.
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| 5. |
D'Onofrio, Brian M. Van Hulle, Carol A. Goodnight, Jackson A. Rathouz, Paul J. Lahey, Benjamin B. |
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Is Maternal Smoking During Pregnancy a Causal Environmental Risk Factor for Adolescent Antisocial Behavior? Testing Etiological Theories and Assumptions Psychological Medicine 42,7 (July 2012): 1535-1545. Also: http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8594215&fulltextType=RA&fileId=S0033291711002443 Cohort(s): NLSY79, NLSY79 Young Adult Publisher: Cambridge University Press Keyword(s): Adolescent Behavior; Crime; Delinquency/Gang Activity; Pre/post Natal Behavior; Smoking (see Cigarette Use) Permission to reprint the abstract has not been received from the publisher. Background: Although many studies indicate that maternal smoking during pregnancy (SDP) is correlated with later offspring antisocial behavior (ASB), recent quasi-experimental studies suggest that background familial factors confound the association. The present study sought to test alternative etiological hypotheses using multiple indices of adolescent ASB, comparing differentially exposed siblings, and testing assumptions in the sibling-comparison design. Method: The study examined the association between maternal SDP and adolescent-reported ASB, criminal convictions and membership in a group of individuals with early-starting and chronic ASB among 6066 offspring of women from the National Longitudinal Survey of Youth, a representative sample of women in the USA. The analyses controlled for statistical covariates and examined associations while comparing differentially exposed siblings. Results: At the population level, each additional pack of cigarettes per day predicted greater mean adolescent-reported ASB symptoms [ratio of means 1.15, 95% confidence interval (CI) 1.08–1.22], odds of being in the top 10% of ASB [odds ratio (OR) 1.34, 95% CI 1.10–1.65], hazard of a criminal conviction [hazard ratio (HR) 1.51, 95% CI 1.34–1.68] and odds of chronic ASB (OR 1.57, 95% CI 1.25–1.99). SDP robustly predicted most assessments of ASB while controlling for measured covariates. When siblings exposed to differing levels of SDP were compared, however, all of the associations were attenuated and were not statistically significant: adolescent-reported mean ASB (ratio of means 0.86, 95% CI 0.74–1.01), high ASB (OR 0.67, 95% CI 0.41–1.12), criminal conviction (HR 0.98, 95% CI 0.66–1.44) and chronic ASB (OR 0.80, 95% CI 0.46–1.38). Conclusions: The results strongly suggest that familial factors account for the correlation between SDP and offspring adolescent ASB, rather than a putative causal environmental influence of SDP. |
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Bibliography Citation
D'Onofrio, Brian M., Carol A. Van Hulle, Jackson A. Goodnight, Paul J. Rathouz and Benjamin B. Lahey. "Is Maternal Smoking During Pregnancy a Causal Environmental Risk Factor for Adolescent Antisocial Behavior? Testing Etiological Theories and Assumptions." Psychological Medicine 42,7 (July 2012): 1535-1545.
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| 6. |
D'Onofrio, Brian M. Van Hulle, Carol A. Waldman, Irwin D. Rodgers, Joseph Lee Harden, K. Paige Rathouz, Paul J. Lahey, Benjamin B. |
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Smoking During Pregnancy And Offspring Externalizing Problems: An Exploration of Genetic and Environmental Confounds Development and Psychopathology 20,1 (Winter 2008): 139-164. Also: http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=1641960&fulltextType=RA&fileId=S0954579408000072 Cohort(s): Children of the NLSY79, NLSY79 Publisher: Cambridge University Press Keyword(s): Attention/Attention Deficit; Behavior Problems Index (BPI); Behavioral Problems; Cigarette Use (see Smoking); Genetics; Pregnancy and Pregnancy Outcomes; Smoking (see Cigarette Use); Variables, Independent - Covariate Permission to reprint the abstract has not been received from the publisher. Previous studies have documented that smoking during pregnancy (SDP) is associated with offspring externalizing problems, even when measured covariates were used to control for possible confounds. However, the association may be because of nonmeasured environmental and genetic factors that increase risk for offspring externalizing problems. The current project used the National Longitudinal Survey of Youth and their children, ages 4-10 years, to explore the relations between SDP and offspring conduct problems (CPs), oppositional defiant problems (ODPs), and attention-deficit/hyperactivity problems (ADHPs) using methodological and statistical controls for confounds. When offspring were compared to their own siblings who differed in their exposure to prenatal nicotine, there was no effect of SDP on offspring CP and ODP. This suggests that SDP does not have a causal effect on offspring CP and ODP. There was a small association between SDP and ADHP, consistent with a causal effect of SDP, but the magnitude of the association was greatly reduced by methodological and statistical controls. Genetically informed analyses suggest that unmeasured environmental variables influencing both SDP and offspring externalizing behaviors account for the previously observed associations. That is, the current analyses imply that important unidentified environmental factors account for the association between SDP and offspring externalizing problems, not teratogenic effects of SDP. |
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Bibliography Citation
D'Onofrio, Brian M., Carol A. Van Hulle, Irwin D. Waldman, Joseph Lee Rodgers, K. Paige Harden, Paul J. Rathouz and Benjamin B. Lahey. "Smoking During Pregnancy And Offspring Externalizing Problems: An Exploration of Genetic and Environmental Confounds." Development and Psychopathology 20,1 (Winter 2008): 139-164.
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| 7. |
D'Onofrio, Brian M. Van Hulle, Carol A. Waldman, Irwin D. Rodgers, Joseph Lee Rathouz, Paul J. Lahey, Benjamin B. |
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Causal Inferences Regarding Prenatal Alcohol Exposure and Childhood Externalizing Problems Archives of General Psychiatry 64,11 (November 2007): 1296-1304. Also: http://archpsyc.ama-assn.org/cgi/content/abstract/64/11/1296 Cohort(s): Children of the NLSY79, NLSY79 Publisher: American Medical Association Keyword(s): Alcohol Use; Behavior Problems Index (BPI); Behavioral Problems; Cognitive Ability; Epidemiology; Genetics; Pre/post Natal Behavior; Pregnancy and Pregnancy Outcomes; Variables, Independent - Covariate Permission to reprint the abstract has not been received from the publisher. CONTEXT: Existing research on the neurobehavioral consequences of prenatal alcohol exposure (PAE) has not adequately accounted for genetic and environmental confounds. OBJECTIVE: To examine the association between PAE and offspring externalizing problems in a large representative sample of families in the United States using measured covariates and a quasi-experimental design to account for unmeasured genetic and environmental confounds. DESIGN: This study combines information from the National Longitudinal Survey of Youth and the Children of the National Longitudinal Survey of Youth. The analyses statistically controlled for measured characteristics of the mothers and families and exposure to other prenatal psychoactive substances. In the primary analyses, siblings differentially exposed to prenatal alcohol were compared. SETTING AND PARTICIPANTS: Women were recruited from the community using a stratified and clustered probability sample and were followed longitudinally. The sample included 8621 offspring of 4912 mothers. MAIN OUTCOME MEASURES: Maternal report of conduct problems (CPs) and attention/impulsivity problems (AIPs) during childhood (ages 4-11 years) using standardized assessments related to psychiatric diagnoses. RESULTS: There was an association between PAE and offspring CPs that was independent of confounded genetic and fixed environmental effects and the measured covariates. The CPs in children of mothers who drank daily during pregnancy were 0.35 SD greater than those in children whose mothers never drank during pregnancy. Although AIPs were associated with PAE when comparing unrelated offspring, children whose mothers drank more frequently during pregnancy did not have more AIPs than siblings who were less exposed to alcohol in utero. Additional subsample analyses suggested that maternal polysubstance use during pregnancy may account for the associations between PAE and AIPs. CONCLUSION: These results are consistent with PAE exerting an environment ally mediated causal effect on childhood CPs, but the relation between PAE and AIPs is more likely to be caused by other factors correlated with maternal drinking during pregnancy. |
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Bibliography Citation
D'Onofrio, Brian M., Carol A. Van Hulle, Irwin D. Waldman, Joseph Lee Rodgers, Paul J. Rathouz and Benjamin B. Lahey. "Causal Inferences Regarding Prenatal Alcohol Exposure and Childhood Externalizing Problems." Archives of General Psychiatry 64,11 (November 2007): 1296-1304.
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| 8. |
Donahue, Kelly L. Van Hulle, Carol A. Rodgers, Joseph Lee D'Onofrio, Brian M. |
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Psychosocial Predictors of Adolescent Sexual Risk Behavior: A Quasi-Experimental Analysis in a Nationally Representative Sample of American Youths Journal of Adolescent Health 54,2 (February 2014): S15-S16. Also: http://www.jahonline.org/article/S1054-139X%2813%2900581-8/fulltext Cohort(s): Children of the NLSY79, NLSY79 Young Adult Publisher: Elsevier Keyword(s): Adolescent Behavior; Age at First Intercourse; Behavior Problems Index (BPI); CESD (Depression Scale); Dating; Depression (see also CESD); Genetics; Kinship; Sexual Activity; Siblings Participants were drawn from the Children of the National Longitudinal Survey of Youth, a longitudinal, nationally representative, and genetically informative sample in the United States (N = 7,743). Using a sibling comparison approach, we tested whether associations between measures of childhood psychosocial adjustment (i.e., early dating, substance use, and emotional and behavioral problems) and adolescent sexual risk behavior (i.e., early age at first intercourse and number of past-year sexual partners) remained after controlling for confounds shared by full siblings and maternal half siblings who differed in their exposure to each risk factor. Next, using quantitative genetic modeling, we also estimated the extent to which these associations were attributable to shared genetic, shared environmental, or nonshared environmental influences. |
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Bibliography Citation
Donahue, Kelly L., Carol A. Van Hulle, Joseph Lee Rodgers and Brian M. D'Onofrio. "Psychosocial Predictors of Adolescent Sexual Risk Behavior: A Quasi-Experimental Analysis in a Nationally Representative Sample of American Youths." Journal of Adolescent Health 54,2 (February 2014): S15-S16.
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| 9. |
Ellingson, Jarrod M. Goodnight, Jackson A. Van Hulle, Carol A. Waldman, Irwin D. D'Onofrio, Brian M. |
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A Sibling-Comparison Study of Smoking During Pregnancy and Childhood Psychological Traits Behavior Genetics 44,1 (January 2014): 25-35. Also: http://link.springer.com/article/10.1007/s10519-013-9618-6 Cohort(s): Children of the NLSY79, NLSY79 Publisher: Behavior Genetics Association Keyword(s): Behavior Problems Index (BPI); Cigarette Use (see Smoking); Intergenerational Patterns/Transmission; Modeling, Growth Curve/Latent Trajectory Analysis; Mothers, Behavior; Mothers, Health; Peabody Individual Achievement Test (PIAT- Math); Peabody Individual Achievement Test (PIAT- Reading); Peabody Picture Vocabulary Test (PPVT); Pre-natal Care/Exposure; Pre/post Natal Behavior; Siblings; Smoking (see Cigarette Use); Temperament Permission to reprint the abstract has not been received from the publisher. Prenatal exposure to substances of abuse is associated with numerous psychological problems in offspring, but quasi-experimental studies controlling for co-occurring risk factors suggest that familial factors (e.g., genetic and environmental effects shared among siblings) confound many associations with maternal smoking during pregnancy (SDP). Few of the quasi-experimental studies in this area have explored normative psychological traits in early childhood or developmental changes across the lifespan, however. The current study used multilevel growth curve models with a large, nationally-representative sample in the United States to investigate for potential effects of SDP on the developmental trajectories of cognitive functioning, temperament/personality, and disruptive behavior across childhood, while accounting for shared familial confounds by comparing differentially exposed siblings and statistically controlling for offspring-specific covariates. Maternal SDP predicted the intercept (but not change over time) for all cognitive and externalizing outcomes. Accounting for familial confounds, however, attenuated the association between SDP exposure and all outcomes, except the intercept (age 5) for reading recognition. These findings, which are commensurate with previous quasi-experimental research on more severe indices of adolescent and adult problems, suggest that the associations between SDP and developmental traits in childhood are due primarily to confounding factors and not a causal association. |
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Bibliography Citation
Ellingson, Jarrod M., Jackson A. Goodnight, Carol A. Van Hulle, Irwin D. Waldman and Brian M. D'Onofrio. "A Sibling-Comparison Study of Smoking During Pregnancy and Childhood Psychological Traits." Behavior Genetics 44,1 (January 2014): 25-35.
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| 10. |
Goodnight, Jackson A. D'Onofrio, Brian M. Cherlin, Andrew J. Emery, Robert E. Van Hulle, Carol A. Lahey, Benjamin B. |
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Effects of Multiple Maternal Relationship Transitions on Offspring Antisocial Behavior in Childhood and Adolescence: A Cousin-Comparison Analysis Journal of Abnormal Child Psychology 41,2 (February 2013): 185-198. Also: http://link.springer.com/article/10.1007/s10802-012-9667-y Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult Publisher: Springer Keyword(s): Armed Forces Qualifications Test (AFQT); Behavior Problems Index (BPI); Behavior, Antisocial; Birth Order; Delinquency/Gang Activity; Genetics; Kinship; Marital Instability; Modeling, Multilevel; Parental Influences; Pre-natal Care/Exposure; Siblings Permission to reprint the abstract has not been received from the publisher. Previous studies of the association between multiple parental relationship transitions (i.e., when a parent begins or terminates an intimate relationship involving cohabitation) and offspring antisocial behavior have varied in their efforts to rule out confounding influences, such as parental antisocial behavior and low income. They also have been limited in the representativeness of their samples. Thus, it remains unclear to what degree parents’ multiple relationship transitions have independent effects on children’s antisocial behavior. Analyses were conducted using data on 8,652 6–9-year-old, 6,911 10–13-year-old, and 6,495 14–17-year-old offspring of a nationally representative sample of U.S. women. Cousin-comparisons were used in combination with statistical covariates to evaluate the associations between maternal relationship transitions and offspring antisocial behavior in childhood and adolescence. Cousin-comparisons suggested that associations between maternal relationship transitions and antisocial behavior in childhood and early adolescence are largely explained by confounding factors. In contrast, the associations between maternal relationship transitions and offspring delinquency in late adolescence were robust to measured and unmeasured confounds. The present findings suggest that interventions aimed at reducing exposure to parental relationship transitions or addressing the psychosocial consequences of exposure to parental relationship transitions could reduce risk for offspring delinquency in late adolescence. |
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Bibliography Citation
Goodnight, Jackson A., Brian M. D'Onofrio, Andrew J. Cherlin, Robert E. Emery, Carol A. Van Hulle and Benjamin B. Lahey. "Effects of Multiple Maternal Relationship Transitions on Offspring Antisocial Behavior in Childhood and Adolescence: A Cousin-Comparison Analysis." Journal of Abnormal Child Psychology 41,2 (February 2013): 185-198.
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| 11. |
Goodnight, Jackson A. Donahue, Kelly L Waldman, Irwin D. Van Hulle, Carol A. Rathouz, Paul J. Lahey, Benjamin B. D'Onofrio, Brian M. |
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Genetic and Environmental Contributions to Associations between Infant Fussy Temperament and Antisocial Behavior in Childhood and Adolescence Behavior Genetics 46,5 (September 2016): 680-692. Also: http://link.springer.com/article/10.1007/s10519-016-9794-2 Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult Publisher: Behavior Genetics Association Keyword(s): Behavior Problems Index (BPI); Behavior, Antisocial; Children, Temperament; Delinquency/Gang Activity; Genetics; Kinship; Modeling, Biometric; Modeling, Multilevel; Siblings Permission to reprint the abstract has not been received from the publisher. Previous research suggests that fussy temperament in infancy predicts risk for later antisocial behavior (ASB) in childhood and adolescence. It remains unclear, however, to what extent infant fussiness is related to later ASB through causal processes or if they both reflect the same family risk factors for ASB. The current study used two approaches, the comparison of siblings and bivariate biometric modeling, to reduce familial confounding and examine genetic and environmental influences on associations between fussiness in the first 2 years of life and ASB in childhood and late adolescence. Analyses were conducted on data from a prospective cohort (9237 at 4–9 years and 7034 at 14–17 years) who are the offspring of a nationally representative sample of US women. In the full sample, fussiness predicted both child and adolescent ASB to small but significant extents, controlling for a wide range of measured child and family-level covariates. When siblings who differed in their fussiness were compared, fussiness predicted ASB in childhood, but not ASB during adolescence. Furthermore, results from a bivariate Cholesky model suggested that even the association of fussiness with childhood ASB found when comparing siblings is attributable to familial factors. That is, although families with infants who are higher in fussiness also tend to have children and adolescents who engage in greater ASB, the hypothesis that infant fussiness has an environmentally mediated impact on the development of future ASB was not strongly supported. |
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Bibliography Citation
Goodnight, Jackson A., Kelly L Donahue, Irwin D. Waldman, Carol A. Van Hulle, Paul J. Rathouz, Benjamin B. Lahey and Brian M. D'Onofrio. "Genetic and Environmental Contributions to Associations between Infant Fussy Temperament and Antisocial Behavior in Childhood and Adolescence." Behavior Genetics 46,5 (September 2016): 680-692.
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Goodnight, Jackson A. Lahey, Benjamin B. Van Hulle, Carol A. Rodgers, Joseph Lee Rathouz, Paul J. Waldman, Irwin D. D'Onofrio, Brian M. |
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A Quasi-Experimental Analysis of the Influence of Neighborhood Disadvantage on Child and Adolescent Conduct Problems Journal of Abnormal Psychology 121,1 (February 2012): 95-108. Also: http://www.ncbi.nlm.nih.gov/pubmed/21942334 Cohort(s): Children of the NLSY79, NLSY79 Publisher: American Psychological Association (APA) Keyword(s): Alcohol Use; Armed Services Vocational Aptitude Battery (ASVAB); Behavior Problems Index (BPI); Behavior, Antisocial; Birth Order; Delinquency/Gang Activity; Family Characteristics; Family Income; Gender Differences; Kinship; Modeling, Multilevel; Mothers, Behavior; Neighborhood Effects; Siblings; Variables, Independent - Covariate A quasi-experimental comparison of cousins differentially exposed to levels of neighborhood disadvantage (ND) was used with extensive measured covariates to test the hypothesis that neighborhood risk has independent effects on youth conduct problems (CPs). Multilevel analyses were based on mother-rated ND and both mother-reported CPs across 4-13 years (n = 7,077) and youth-reported CPs across 10-13 years (n = 4,524) from the Children of the National Longitudinal Survey of Youth. ND was robustly related to CPs reported by both informants when controlling for both measured risk factors that are correlated with ND and unmeasured confounds. These findings are consistent with the hypothesis that ND has influence on conduct problems. |
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Bibliography Citation
Goodnight, Jackson A., Benjamin B. Lahey, Carol A. Van Hulle, Joseph Lee Rodgers, Paul J. Rathouz, Irwin D. Waldman and Brian M. D'Onofrio. "A Quasi-Experimental Analysis of the Influence of Neighborhood Disadvantage on Child and Adolescent Conduct Problems." Journal of Abnormal Psychology 121,1 (February 2012): 95-108.
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Harden, K. Paige D'Onofrio, Brian M. Van Hulle, Carol A. Turkheimer, Eric Rodgers, Joseph Lee Waldman, Irwin D. Lahey, Benjamin B. |
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Population Density And Youth Antisocial Behavior Journal of Child Psychology and Psychiatry 50,8 (2009): 999-1008. Also: http://journals.ohiolink.edu.proxy.lib.ohio-state.edu/ejc/pdf.cgi/Paige_Harden_K.pdf?issn=00219630&issue=v50i0008&article=999_pdayab Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult Publisher: Blackwell Publishing, Inc. => Wiley Online Keyword(s): Age at First Birth; Armed Forces Qualifications Test (AFQT); Armed Services Vocational Aptitude Battery (ASVAB); Bayesian; Behavior Problems Index (BPI); Child Self-Administered Supplement (CSAS); Delinquency/Gang Activity; Depression (see also CESD); Ethnic Differences; Geocoded Data; Kinship; Modeling, Multilevel; Mothers, Behavior; Neighborhood Effects; Pre/post Natal Behavior; Racial Differences; Smoking (see Cigarette Use); Urbanization/Urban Living Theoretical models concerning how neighborhood contexts adversely influence juvenile antisocial behavior frequently focus on urban neighborhoods; however, previous studies comparing urban and rural areas on the prevalence of youth antisocial behavior have yielded mixed results. The current study uses longitudinal data on the offspring of a nationally representative sample of mothers (N = 4,886) in the US. There was no relation between density and mother-reported child conduct problems across ages 4–13 years, but youth living in areas of greater population density exhibited more youth self-reported delinquency across 10–17 years. Families often moved to counties with greater or lesser population density, but longitudinal analyses treating population density as a time-varying covariate did not support the hypothesis that living in densely populated counties influenced youth delinquency. Rather, the association between population density and delinquency appears to be due to unmeasured selection variables that differ between families who live in more or less densely populated counties. (PsycINFO Database Record (c) 2009 APA, all rights reserved) |
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Bibliography Citation
Harden, K. Paige, Brian M. D'Onofrio, Carol A. Van Hulle, Eric Turkheimer, Joseph Lee Rodgers, Irwin D. Waldman and Benjamin B. Lahey. "Population Density And Youth Antisocial Behavior." Journal of Child Psychology and Psychiatry 50,8 (2009): 999-1008.
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| 14. |
Jaffee, Sara R. Van Hulle, Carol A. Rodgers, Joseph Lee |
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Effects of Nonmaternal Care in the First 3 Years on Children's Academic Skills and Behavioral Functioning in Childhood and Early Adolescence: A Sibling Comparison Study Child Development 82,4 (July/August 2011): 1076–1091. Also: http://onlinelibrary.wiley.com/doi/10.1111/j.1467-8624.2011.01611.x/abstract Cohort(s): Children of the NLSY79 Publisher: Blackwell Publishing, Inc. => Wiley Online Keyword(s): Behavior Problems Index (BPI); Behavior, Antisocial; Child Care; Kinship; Maternal Employment; Modeling, Fixed Effects; Modeling, Multilevel; Mothers, Behavior; Peabody Individual Achievement Test (PIAT- Math); Peabody Individual Achievement Test (PIAT- Reading); Siblings; Temperament Nonmaternal care of infant children is increasingly common, but there is disagreement as to whether it is harmful for children. Using data from 9,185 children (5 years and older) who participated in the Children of the National Longitudinal Survey of Youth, the current study compared 2 groups: those for whom nonmaternal care was initiated in the first 3 years and those for whom it was not. Between-family comparisons showed that early nonmaternal care was associated with higher achievement and lower behavior problem scores in childhood and adolescence. However, within-family comparisons failed to detect differences between siblings who had different early nonmaternal care experiences. The study concludes that the timing of entry to nonmaternal care in the first 3 years has neither positive nor negative effects on children's outcomes. © 2011 The Authors. Child Development © 2011 Society for Research in Child Development, Inc. |
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Bibliography Citation
Jaffee, Sara R., Carol A. Van Hulle and Joseph Lee Rodgers. "Effects of Nonmaternal Care in the First 3 Years on Children's Academic Skills and Behavioral Functioning in Childhood and Early Adolescence: A Sibling Comparison Study." Child Development 82,4 (July/August 2011): 1076–1091. A.
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| 15. |
Lahey, Benjamin B. D'Onofrio, Brian M. Van Hulle, Carol A. Rathouz, Paul J. |
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Prospective Association of Childhood Receptive Vocabulary and Conduct Problems with Self-Reported Adolescent Delinquency: Tests of Mediation and Moderation in Sibling-Comparison Analyses Journal of Abnormal Child Psychology 42,8 (November 2014): 1341-1351. Also: http://link.springer.com/article/10.1007/s10802-014-9873-x Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult Publisher: Springer Keyword(s): Behavior Problems Index (BPI); Behavior, Antisocial; Birth Order; Delinquency/Gang Activity; Family Characteristics; Kinship; Modeling, Multilevel; Peabody Picture Vocabulary Test (PPVT); Scale Construction; Siblings Permission to reprint the abstract has not been received from the publisher. Associations among receptive vocabulary measured at 4-9 years, mother-reported childhood conduct problems at 4-9 years, and self-reported adolescent delinquency at 14-17 years were assessed using data from a prospective study of the offspring of a large U.S. nationally representative sample of women. A novel quasi-experimental strategy was used to rule out family-level confounding by estimating path-analytic associations within families in a sibling comparison design. This allowed simultaneous tests of the direct and indirect effects of receptive vocabulary and childhood conduct problems, and of their joint moderation, on adolescent delinquency without family-level environmental confounding. The significant association of receptive vocabulary with later adolescent delinquency was indirect, mediated by childhood conduct problems. Furthermore, a significant interaction between receptive vocabulary and childhood conduct problems reflected a steeper slope for the predictive association between childhood conduct problems and adolescent delinquency when receptive vocabulary scores were higher. These findings of significant indirect association were qualitatively identical in both population-level and within-family analyses, suggesting that they are not the result of family-level confounds. |
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Bibliography Citation
Lahey, Benjamin B., Brian M. D'Onofrio, Carol A. Van Hulle and Paul J. Rathouz. "Prospective Association of Childhood Receptive Vocabulary and Conduct Problems with Self-Reported Adolescent Delinquency: Tests of Mediation and Moderation in Sibling-Comparison Analyses." Journal of Abnormal Child Psychology 42,8 (November 2014): 1341-1351.
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| 16. |
Lahey, Benjamin B. Van Hulle, Carol A. D'Onofrio, Brian M. Rodgers, Joseph Lee Waldman, Irwin D. |
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Is Parental Knowledge of their Adolescent Offspring's Whereabouts and Peer Associations Spuriously Associated with Offspring Delinquency? Journal of Abnormal Child Psychology 36,6 (August 2008): 807-823. Online: January 24, 2008. Also: http://www.springerlink.com/content/x636801136356128/?p=ace6e76807404b8d857fdf594a5c0a8f&pi=0 Cohort(s): Children of the NLSY79, NLSY79 Young Adult Publisher: Springer Keyword(s): Adolescent Behavior; Child Self-Administered Supplement (CSAS); Delinquency/Gang Activity; Neighborhood Effects; Parent Supervision/Monitoring; Parent-Child Interaction; Parental Influences; Peers/Peer influence/Peer relations; Variables, Independent - Covariate Permission to reprint the abstract has not been received from the publisher. Recent studies suggest that most of what parents know about their adolescent offspring's whereabouts and companions is the result of youth disclosure, rather than information gained through active parental monitoring. This raises the possibility that parental knowledge is spuriously correlated with youth delinquency solely because the most delinquent youth disclose the least information to parents (because they have the most to hide). We tested this spurious association hypothesis using prospective data on offspring of a nationally representative sample of US women, controlling demographic and contextual covariates. In separate analyses, greater parental knowledge of their offspring's peer associations at both 12–13 years and at 14–15 years was associated with lower odds of being in the top 1 standard deviation of youth-reported delinquency at 16–17 years, controlling for delinquency at the earlier ages. The extent to which parents set limits on activities with peers at 14–15 years did not mediate or moderate the association between parental knowledge and delinquency, but it did independently predict future delinquency among adolescents living in high-risk neighborhoods. This suggests that the association between parental knowledge and future delinquency is not solely spurious; rather parental knowledge and limit setting are both meaningful predictors of future delinquency. |
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Bibliography Citation
Lahey, Benjamin B., Carol A. Van Hulle, Brian M. D'Onofrio, Joseph Lee Rodgers and Irwin D. Waldman. "Is Parental Knowledge of their Adolescent Offspring's Whereabouts and Peer Associations Spuriously Associated with Offspring Delinquency?" Journal of Abnormal Child Psychology 36,6 (August 2008): 807-823. Online: January 24, 2008.
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| 17. |
Lahey, Benjamin B. Van Hulle, Carol A. Keenan, Kate Rathouz, Paul J. D'Onofrio, Brian M. Rodgers, Joseph Lee Waldman, Irwin D. |
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Temperament and Parenting during the First Year of Life Predict Future Child Conduct Problems Journal of Abnormal Child Psychology 36,8 (November 2008): 1139-1158 Cohort(s): Children of the NLSY79 Publisher: Springer Keyword(s): Behavior Problems Index (BPI); Home Observation for Measurement of Environment (HOME); Infants; Parent-Child Interaction; Parental Influences; Temperament Permission to reprint the abstract has not been received from the publisher. Predictive associations between parenting and temperament during the first year of life and child conduct problems were assessed longitudinally in 1,863 offspring of a representative sample of women. Maternal ratings of infant fussiness, activity level, predictability, and positive affect each independently predicted maternal ratings of conduct problems during ages 4–13 years. Furthermore, a significant interaction indicated that infants who were both low in fussiness and high in predictability were at very low risk for future conduct problems. Fussiness was a stronger predictor of conduct problems in boys whereas fearfulness was a stronger predictor in girls. Conduct problems also were robustly predicted by low levels of early mother-report cognitive stimulation when infant temperament was controlled. Interviewer-rated maternal responsiveness was a robust predictor of conduct problems, but only among infants low in fearfulness. Spanking during infancy predicted slightly more severe conduct problems, but the prediction was moderated by infant fussiness and positive affect. Thus, individual differences in risk for mother-rated conduct problems across childhood are already partly evident in maternal ratings of temperament during the first year of life and are predicted by early parenting and parenting-by-temperament interactions. |
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Bibliography Citation
Lahey, Benjamin B., Carol A. Van Hulle, Kate Keenan, Paul J. Rathouz, Brian M. D'Onofrio, Joseph Lee Rodgers and Irwin D. Waldman. "Temperament and Parenting during the First Year of Life Predict Future Child Conduct Problems." Journal of Abnormal Child Psychology 36,8 (November 2008): 1139-1158.
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| 18. |
Lahey, Benjamin B. Van Hulle, Carol A. Waldman, Irwin D. Rodgers, Joseph Lee D'Onofrio, Brian M. Pedlow, Steven Rathouz, Paul J. Keenan, Kate |
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Testing Descriptive Hypotheses Regarding Sex Differences in the Development of Conduct Problems and Delinquency Journal of Abnormal Child Psychology 34,5 (October 2006): 737-755. Also: http://www.springerlink.com/content/j1716gl8501w8082/ Cohort(s): Children of the NLSY79, NLSY79 Young Adult Publisher: Springer Keyword(s): Adolescent Behavior; Behavior Problems Index (BPI); Delinquency/Gang Activity; Intergenerational Patterns/Transmission; Peabody Individual Achievement Test (PIAT- Reading); Peabody Picture Vocabulary Test (PPVT); Temperament Permission to reprint the abstract has not been received from the publisher. Accurate descriptions of sex differences in the development of childhood conduct problems and adolescent delinquency will inform theories of their causes in fundamentally important ways. Using data on 4,572 offspring of a national sample of women, we tested descriptive hypotheses regarding sex differences. As predicted, the magnitude of sex differences varied with age, suggesting that multiple processes differentially influence levels of these behaviors in females and males across development. During childhood, boys scored lower on measures of cognitive ability and exhibited lower sociability and compliance and greater hyperactivity, oppositional behavior, and conduct problems. Most of these variables were associated with childhood conduct problems and adolescent delinquency equally in females and males, but maternal delinquency and early childhood sociability were correlated more strongly with childhood conduct problems in males and childhood compliance predicted adolescent delinquency more strongly in females. Both sexes exhibited both childhood-onset and adolescent-onset trajectories of delinquency. Although more males followed a childhood-onset trajectory, there were few sex differences in the early childhood risk correlates of either delinquency trajectory. |
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Bibliography Citation
Lahey, Benjamin B., Carol A. Van Hulle, Irwin D. Waldman, Joseph Lee Rodgers, Brian M. D'Onofrio, Steven Pedlow, Paul J. Rathouz and Kate Keenan. "Testing Descriptive Hypotheses Regarding Sex Differences in the Development of Conduct Problems and Delinquency ." Journal of Abnormal Child Psychology 34,5 (October 2006): 737-755.
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| 19. |
Mendle, Jane Harden, K. Paige Turkheimer, Eric Van Hulle, Carol A. D'Onofrio, Brian M. Brooks-Gunn, Jeanne Rodgers, Joseph Lee Emery, Robert E. Lahey, Benjamin B. |
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Associations Between Father Absence and Age of First Sexual Intercourse Child Development 80,5 (September/October 2009): 1463-1480. Also: http://onlinelibrary.wiley.com/doi/10.1111/j.1467-8624.2009.01345.x/abstract Cohort(s): NLSY79 Young Adult Publisher: Blackwell Publishing, Inc. => Wiley Online Keyword(s): Adolescent Sexual Activity; Age at First Intercourse; Family Structure; Fathers, Absence; Genetics; Kinship; Sexual Activity; Siblings Children raised without a biological father in the household have earlier average ages of first sexual intercourse than children raised in father-present households. Competing theoretical perspectives have attributed this either to effects of father absence on socialization and physical maturation or to nonrandom selection of children predisposed for early sexual intercourse into father-absent households. Genetically informative analyses of the children of sister dyads (N = 1,382, aged 14–21 years) support the selection hypothesis: This association seems attributable to confounded risks, most likely genetic in origin, which correlated both with likelihood of father absence and early sexual behavior. This holds implications for environmental theories of maturation and suggests that previous research may have inadvertently overestimated the role of family structure in reproductive maturation. |
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Bibliography Citation
Mendle, Jane, K. Paige Harden, Eric Turkheimer, Carol A. Van Hulle, Brian M. D'Onofrio, Jeanne Brooks-Gunn, Joseph Lee Rodgers, Robert E. Emery and Benjamin B. Lahey. "Associations Between Father Absence and Age of First Sexual Intercourse." Child Development 80,5 (September/October 2009): 1463-1480.
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| 20. |
Mendle, Jane Harden, K. Paige Van Hulle, Carol A. D'Onofrio, Brian M. Lahey, Benjamin B. Rodgers, Joseph Lee Emery, Robert E. Turkheimer, Eric |
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Father Absence and Early Sexual Activity: Revisiting Evolutionary Theories Presented: Amsterdam, The Netherlands, Behavior Genetics Association 37th Annual Meeting, June 5, 2007. Cohort(s): NLSY79 Young Adult Publisher: Behavior Genetics Association Keyword(s): Adolescent Sexual Activity; Age at First Intercourse; Fathers, Absence; Genetics; Kinship; Modeling, Multilevel; Sexual Activity; Siblings Permission to reprint the abstract has not been received from the publisher. Children raised without a biological father present in the household are more likely to exhibit precocious and risky sexual behavior during adolescence. Most explanations for this association invoke an evolutionary mechanism: individuals have evolved such that early childhood environment influences the particular reproductive strategies manifest later in life. The developmental pathways presaging adult reproductive behavior are especially sensitive to the father's family role and the quality of paternal care is believed to affect sexual development independent of other stressors in the family system. Although these theories conceptualize early sexual activity as a consequence of familial stress, a genetic predisposition for risky sexual behavior may manifest in father absence in parents and in precocious sexual maturation in children. One means of clarifying the role of father absence in timing of first intercourse is through studying offspring of twins and/or sisters. If the association between timing of intercourse and paternal absence is an artifact of familial risk, the age of first intercourse in children of discordant sibling dyads will be comparable -- despite the differing environmental circumstances in which these cousins were raised. This alternative hypothesis was tested in a sample of adolescent children from the National Longitudinal Survey of Youth (NLSY), using multilevel survival models adapted from the more common children of-twins (CoT) design. Results were not consistent with a causal role of father absence on offspring sexuality; children who experienced father absence did not differ in age of first intercourse from either siblings or cousins raised with present fathers. But, these children did differ from those who had no father absence in either their nuclear or extended family. This suggests that it is not father absence, per se, but rather some familial factor correlated with father absence that produces this association. |
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Bibliography Citation
Mendle, Jane, K. Paige Harden, Carol A. Van Hulle, Brian M. D'Onofrio, Benjamin B. Lahey, Joseph Lee Rodgers, Robert E. Emery and Eric Turkheimer. "Father Absence and Early Sexual Activity: Revisiting Evolutionary Theories." Presented: Amsterdam, The Netherlands, Behavior Genetics Association 37th Annual Meeting, June 5, 2007. |
| 21. |
Rodgers, Joseph Lee Van Hulle, Carol A. D'Onofrio, Brian M. Rathouz, Paul J. Beasley, Will Johnson, Amber Waldman, Irwin D. Lahey, Benjamin B. |
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Behavior Problems and Timing of Menarche: A Developmental Longitudinal Biometrical Analysis Using the NLSY-Children Data Behavior Genetics 45,1 (January 2015): 51-70. Also: http://link.springer.com/article/10.1007/s10519-014-9676-4 Cohort(s): Children of the NLSY79, NLSY79 Young Adult Publisher: Behavior Genetics Association Keyword(s): Age at First Intercourse; Behavior Problems Index (BPI); Behavior, Antisocial; Kinship; Menarche/First Menstruation; Siblings Permission to reprint the abstract has not been received from the publisher. A powerful longitudinal data source, the National Longitudinal Survey of Youth Children data, allows measurement of behavior problems (BP) within a developmental perspective linking them to menarcheal timing (MT). In a preliminary analysis, we evaluate the bivariate relationships between BP measured at different developmental periods and the timing of menarche. Correlations were not consistent with any correlational/causal relationship between BP and MT. In the major part of our study, MT was used to moderate the developmental trajectory of BP, within a genetically-informed design. Girls reaching menarche early had behavior problem variance accounted for by the shared environment; those reaching menarche with average/late timing had behavior problem differences accounted for by genetic variance. Our findings match previous empirical results in important ways, and also extend those results. A theoretical interpretation is offered in relation to a theory linking genetic/shared environmental variance to flexibility and choices available within the family in relation to BP. |
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Bibliography Citation
Rodgers, Joseph Lee, Carol A. Van Hulle, Brian M. D'Onofrio, Paul J. Rathouz, Will Beasley, Amber Johnson, Irwin D. Waldman and Benjamin B. Lahey. "Behavior Problems and Timing of Menarche: A Developmental Longitudinal Biometrical Analysis Using the NLSY-Children Data." Behavior Genetics 45,1 (January 2015): 51-70.
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| 22. |
Sujan, Ayesha C. Class, Quetzal Rickert, Martin E. Van Hulle, Carol A. D'Onofrio, Brian M. |
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Risk Factors and Child Outcomes Associated with Short and Long Interpregnancy Intervals Early Child Development and Care published online (14 December 2019): DOI: 10.1080/03004430.2019.1703111. Also: https://www.tandfonline.com/doi/full/10.1080/03004430.2019.1703111 Cohort(s): Children of the NLSY79, NLSY79 Publisher: Routledge ==> Taylor & Francis (1998) Keyword(s): Behavior Problems Index (BPI); Birth Order; Births, Repeat / Spacing; Child Development; Cognitive Ability; Peabody Picture Vocabulary Test (PPVT); Pregnancy and Pregnancy Outcomes; Siblings; Temperament Previous research assessing consequences of interpregnancy intervals (IPIs) on child development is mixed. Utilizing a population-based US sample (n = 5339), we first estimate the associations between background characteristics (e.g. sociodemographic and maternal characteristics) and short (≤1 year) and long (>3 years) IPI. Then, we estimate associations between IPI and birth outcomes, infant temperament, cognitive ability, and externalizing symptoms. Several background characteristics, such as maternal age at childbearing and previous pregnancy loss, were associated with IPI, indicating research on the putative effects of IPI must account for background characteristics. After covariate adjustment, short IPI was associated with poorer foetal growth and long IPI was associated with lower infant activity level; however, associations between short and long IPI and the other outcomes were neither large nor statistically significant. These findings indicate that rather than intervening to modify IPI, at-risk families may benefit from interventions aimed at other modifiable risk factors. |
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Bibliography Citation
Sujan, Ayesha C., Quetzal Class, Martin E. Rickert, Carol A. Van Hulle and Brian M. D'Onofrio. "Risk Factors and Child Outcomes Associated with Short and Long Interpregnancy Intervals." Early Child Development and Care published online (14 December 2019): DOI: 10.1080/03004430.2019.1703111.
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| 23. |
Sujan, Ayesha C. Rickert, Martin E. Class, Quetzal Coyne, Claire A. Lichtenstein, Paul Almqvist, Catarina Larsson, Henrik Sjölander, Arvid Lahey, Benjamin B. Van Hulle, Carol A. Waldman, Irwin D. Öberg, A. Sara D'Onofrio, Brian M. |
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A Genetically Informed Study of the Associations Between Maternal Age at Childbearing and Adverse Perinatal Outcomes Behavior Genetics 46,3 (May 2016): 431-456. Also: http://link.springer.com/article/10.1007/s10519-015-9748-0/fulltext.html Cohort(s): Children of the NLSY79, NLSY79 Publisher: Springer Keyword(s): Age at Birth; Alcohol Use; Armed Forces Qualifications Test (AFQT); Birth Order; Birth Outcomes; Birthweight; Cross-national Analysis; Delinquency/Gang Activity; Depression (see also CESD); Genetics; Gestation/Gestational weight gain; Kinship; Mothers, Health; Siblings; Substance Use; Sweden, Swedish Permission to reprint the abstract has not been received from the publisher. We examined associations of maternal age at childbearing (MAC) with gestational age and fetal growth (i.e., birth weight adjusting for gestational age), using two genetically informed designs (cousin and sibling comparisons) and data from two cohorts, a population-based Swedish sample and a nationally representative United States sample. We also conducted sensitivity analyses to test limitations of the designs. The findings were consistent across samples and suggested that, associations observed in the population between younger MAC and shorter gestational age were confounded by shared familial factors; however, associations of advanced MAC with shorter gestational age remained robust after accounting for shared familial factors. In contrast to the gestational age findings, neither early nor advanced MAC was associated with lower fetal growth after accounting for shared familial factors. Given certain assumptions, these findings provide support for a causal association between advanced MAC and shorter gestational age. The results also suggest that there are not causal associations between early MAC and shorter gestational age, between early MAC and lower fetal growth, and between advanced MAC and lower fetal growth. |
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Bibliography Citation
Sujan, Ayesha C., Martin E. Rickert, Quetzal Class, Claire A. Coyne, Paul Lichtenstein, Catarina Almqvist, Henrik Larsson, Arvid Sjölander, Benjamin B. Lahey, Carol A. Van Hulle, Irwin D. Waldman, A. Sara Öberg and Brian M. D'Onofrio. "A Genetically Informed Study of the Associations Between Maternal Age at Childbearing and Adverse Perinatal Outcomes." Behavior Genetics 46,3 (May 2016): 431-456.
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| 24. |
Van Hulle, Carol A. Rodgers, Joseph Lee D'Onofrio, Brian M. Waldman, Irwin D. Lahey, Benjamin B. |
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Sex Differences in the Causes of Self-Reported Adolescent Delinquency Journal of Abnormal Psychology 116, 2 (May 2007): 236-248. Also: http://www.sciencedirect.com/science/article/pii/S0021843X07627588 Cohort(s): NLSY79 Young Adult Publisher: American Psychological Association (APA) Keyword(s): Adolescent Behavior; Delinquency/Gang Activity; Gender Differences; Genetics; Siblings Sex differences in the causes of self-reported adolescent delinquency were examined in full and half siblings born to a nationally representative sample of women in the United States. Qualitative sex differences in the genes that influence delinquency were not detected. Similarly, the proportions of variance in both aggressive and nonaggressive delinquency attributable to genetic and environmental influences did not differ significantly between girls and boys. Nonetheless, total variance in delinquency was greater among boys, and a scalar sex-differences model suggested that genetic and environmental influences on delinquency have less effect on population variation in delinquency among girls. Similarly, a test of the polygenic multiple threshold model suggested that girls require greater causal liability for the expression of delinquency than boys. |
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Bibliography Citation
Van Hulle, Carol A., Joseph Lee Rodgers, Brian M. D'Onofrio, Irwin D. Waldman and Benjamin B. Lahey. "Sex Differences in the Causes of Self-Reported Adolescent Delinquency." Journal of Abnormal Psychology 116, 2 (May 2007): 236-248.
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| 25. |
Vaughan, Erikka B. Van Hulle, Carol A. Beasley, William H. Rodgers, Joseph Lee D'Onofrio, Brian M. |
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Clarifying the Associations between Age at Menarche and Adolescent Emotional and Behavioral Problems Journal of Youth and Adolescence 44,4 (April 2015): 922-939. Also: http://link.springer.com/article/10.1007/s10964-015-0255-7 Cohort(s): NLSY79, NLSY79 Young Adult Publisher: Springer Keyword(s): Age at First Intercourse; Age at Menarche/First Menstruation; Behavior Problems Index (BPI); CESD (Depression Scale); Crime; Delinquency/Gang Activity; Kinship; Modeling, Multilevel; Siblings Permission to reprint the abstract has not been received from the publisher. Better understanding risk factors for the development of adolescent emotional and behavioral problems can help with intervention and prevention efforts. Previous studies have found that an early menarcheal age predicts several adolescent problems, including depressive symptoms, delinquency, and early age at first intercourse. Few studies, nevertheless, have explicitly tested (a) whether the associations with menarcheal age vary across racial/ethnic groups or (b) whether the sources of the associations are within-families (i.e., consistent with a direct, causal link) or only between-families (i.e., due to selection or confounding factors). The current study analyzed data from a nationally representative US Sample of females (N=5,637). We examined whether race/ethnicity moderated the associations between early menarche and several adolescent problems by using multiple-group analyses and we examined the degree to which genetic and environmental factors shared by family members account for the associations by comparing sisters and cousins with differing menarcheal ages. Menarcheal age predicted subsequent depressive symptoms, delinquency, and early age at first intercourse in the population. The magnitudes of the associations were similar across all racial/ethnic groups for all outcomes. The within-family associations (i.e., when comparing siblings and cousins with different menarcheal age) were large and statistically significant when predicting early intercourse, but not the other outcomes. The findings suggest that selection or confounding factors account for the associations between menarcheal age and subsequent depressive symptoms and delinquency, whereas the independent association between menarcheal age and early age at first intercourse is consistent with a direct, causal effect. |
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Bibliography Citation
Vaughan, Erikka B., Carol A. Van Hulle, William H. Beasley, Joseph Lee Rodgers and Brian M. D'Onofrio. "Clarifying the Associations between Age at Menarche and Adolescent Emotional and Behavioral Problems." Journal of Youth and Adolescence 44,4 (April 2015): 922-939.
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