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Author: Donahue, Kelly L
Resulting in 3 citations.
1. D'Onofrio, Brian M.
Donahue, Kelly L
Coyne, Claire A.
Van Hulle, Carol A.
Rodgers, Joseph Lee
Waldman, Irwin D.
Lahey, Benjamin B.
Early Maternal Age at Childbearing and Offspring Functioning During Adolescence: A Sibling-Comparison Study of Sexual Behavior and Depression
Presented: Minneapolis MN, Behavior Genetics Association Annual Meeting, 2009
Cohort(s): Children of the NLSY79, NLSY79 Young Adult
Publisher: Behavior Genetics Association
Keyword(s): Age at Birth; Age at First Intercourse; CESD (Depression Scale); Depression (see also CESD); Sexual Activity; Siblings

Permission to reprint the abstract has not been received from the publisher.

Offspring born to younger mothers are at increased risk for problems during adolescence across a range of domains. Previous research suggests that the mechanisms responsible for the associations between offspring adjustment and early maternal age at childbearing (MAC) are dependent on the outcomes being explored. The current study used statistical covariates and the comparison of siblings differentially exposed to MAC to account for alternative explanations for the statistical relations with risky sexual behavior and depression during adolescence. The study included 6,056 offspring (ages 14–21) born to a nationally representative sample of women in the US from the National Longitudinal Survey of Youth and children of the NLSY studies. MAC in the sample ranged from 13- to 34-year-old (M = 23.2). Each increasing year of maternal childbearing was associated with a 14% reduction (OR = 0.86, p\0.001) in the risk of early sexual intercourse (before the age of 14). For instance, offspring born to teenage mothers were 2.46 times more likely to have sex before the age of 14 than offspring born to non-teenage mothers. The association between MAC and early sexual activity remained when controlling for maternal characteristics, such as race/ethnicity, adolescent delinquency, depression, and educational level, and when comparing differentially exposed siblings (OR = .93, p\0.05). Maternal teenage childbearing was also associated with offspring adolescent depression (from ages 14- to 17-year-old), as measured by the CESD (b = -0.04 SD/year at childbearing, p\0.001). The association remained when controlling for maternal covariates and when comparing siblings differentially exposed (b = -0.04 SD/year at childbearing, p\0.001). The results suggest that environmental factors specifically associated with early childbearing account for increased risk of early sexual activity and adolescent depression in offspring.
Bibliography Citation
D'Onofrio, Brian M., Kelly L Donahue, Claire A. Coyne, Carol A. Van Hulle, Joseph Lee Rodgers, Irwin D. Waldman and Benjamin B. Lahey. "Early Maternal Age at Childbearing and Offspring Functioning During Adolescence: A Sibling-Comparison Study of Sexual Behavior and Depression." Presented: Minneapolis MN, Behavior Genetics Association Annual Meeting, 2009.
2. D'Onofrio, Brian M.
Rickert, Martin E.
Langström, Niklas
Donahue, Kelly L
Coyne, Claire A.
Larsson, Henrik
Ellingson, Jarrod M.
Van Hulle, Carol A.
Iliadou, Anastasia N.
Rathouz, Paul J.
Lahey, Benjamin B.
Lichtenstein, Paul
Familial Confounding of the Association Between Maternal Smoking During Pregnancy and Offspring Substance Use and Problems
Archives of General Psychiatry 69,11 (November 2012): 1140-1150.
Also: http://archpsyc.jamanetwork.com/article.aspx?articleid=1389367
Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult
Publisher: American Medical Association
Keyword(s): Adolescent Behavior; Alcohol Use; Birth Order; Child Self-Administered Supplement (CSAS); Cigarette Use (see Smoking); Intergenerational Patterns/Transmission; Mothers, Behavior; Mothers, Health; Pre/post Natal Behavior; Siblings; Smoking (see Cigarette Use); Substance Use; Sweden, Swedish

Permission to reprint the abstract has not been received from the publisher.

Objective: To determine the extent to which the association between SDP and offspring substance use/problems depends on confounded familial background factors by using a quasi-experimental design.

Design: We used 2 separate samples from the United States and Sweden. The analyses prospectively predicted multiple indices of substance use and problems while controlling for statistical covariates and comparing differentially exposed siblings to minimize confounding.

Conclusions: The association between maternal SDP and offspring substance use/problems is likely due to familial background factors, not a causal influence, because siblings have similar rates of substance use and problems regardless of their specific exposure to SDP.

Bibliography Citation
D'Onofrio, Brian M., Martin E. Rickert, Niklas Langström, Kelly L Donahue, Claire A. Coyne, Henrik Larsson, Jarrod M. Ellingson, Carol A. Van Hulle, Anastasia N. Iliadou, Paul J. Rathouz, Benjamin B. Lahey and Paul Lichtenstein. "Familial Confounding of the Association Between Maternal Smoking During Pregnancy and Offspring Substance Use and Problems." Archives of General Psychiatry 69,11 (November 2012): 1140-1150.
3. Goodnight, Jackson A.
Donahue, Kelly L
Waldman, Irwin D.
Van Hulle, Carol A.
Rathouz, Paul J.
Lahey, Benjamin B.
D'Onofrio, Brian M.
Genetic and Environmental Contributions to Associations between Infant Fussy Temperament and Antisocial Behavior in Childhood and Adolescence
Behavior Genetics 46,5 (September 2016): 680-692.
Also: http://link.springer.com/article/10.1007/s10519-016-9794-2
Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult
Publisher: Behavior Genetics Association
Keyword(s): Behavior Problems Index (BPI); Behavior, Antisocial; Children, Temperament; Delinquency/Gang Activity; Genetics; Kinship; Modeling, Biometric; Modeling, Multilevel; Siblings

Permission to reprint the abstract has not been received from the publisher.

Previous research suggests that fussy temperament in infancy predicts risk for later antisocial behavior (ASB) in childhood and adolescence. It remains unclear, however, to what extent infant fussiness is related to later ASB through causal processes or if they both reflect the same family risk factors for ASB. The current study used two approaches, the comparison of siblings and bivariate biometric modeling, to reduce familial confounding and examine genetic and environmental influences on associations between fussiness in the first 2 years of life and ASB in childhood and late adolescence. Analyses were conducted on data from a prospective cohort (9237 at 4–9 years and 7034 at 14–17 years) who are the offspring of a nationally representative sample of US women. In the full sample, fussiness predicted both child and adolescent ASB to small but significant extents, controlling for a wide range of measured child and family-level covariates. When siblings who differed in their fussiness were compared, fussiness predicted ASB in childhood, but not ASB during adolescence. Furthermore, results from a bivariate Cholesky model suggested that even the association of fussiness with childhood ASB found when comparing siblings is attributable to familial factors. That is, although families with infants who are higher in fussiness also tend to have children and adolescents who engage in greater ASB, the hypothesis that infant fussiness has an environmentally mediated impact on the development of future ASB was not strongly supported.
Bibliography Citation
Goodnight, Jackson A., Kelly L Donahue, Irwin D. Waldman, Carol A. Van Hulle, Paul J. Rathouz, Benjamin B. Lahey and Brian M. D'Onofrio. "Genetic and Environmental Contributions to Associations between Infant Fussy Temperament and Antisocial Behavior in Childhood and Adolescence." Behavior Genetics 46,5 (September 2016): 680-692.