Search Results

METHODS: We analyzed 3917 women with 1 to 3 pregnancies in the prospective US National Longitudinal Survey of Youth, from 1979 to 2012. We compared the estimated obesity prevalence between 2 scenarios: gestational weight gain as reported and under the scenario of a hypothetical intervention that all women with excessive gestational weight gain instead gained as recommended by the Institute of Medicine (2009).

RESULTS: A hypothetical intervention was associated with a significantly reduced estimated prevalence of obesity for first (3.3 percentage points; 95% confidence interval [CI] = 1.0, 5.6) and second (3.0 percentage points; 95% CI = 0.7, 5.2) births, and twice as high in Black as in White mothers, but not significant in Hispanics. The population attributable fraction was 10.7% (95% CI = 3.3%, 18.1%) in first and 9.3% (95% CI = 2.2%, 16.5%) in second births.

CONCLUSIONS: Development of effective weight-management interventions for childbearing women could lead to meaningful reductions in long-term obesity.

Methods: We used a multilevel design to examine associations between exposure to state-level unexpected economic contraction during each trimester of gestation and birth weight for gestational age percentile and small for gestational age (SGA), using the National Longitudinal Survey of Youth 1979. We examined differences in observed associations by maternal educational attainment, race/ethnicity, employment status, and poverty status.

Results: Exposure in the first trimester was associated with a 3.7 percentile point decrease in birth weight for gestational age (95% confidence interval [CI] = −6.8 to −0.6). This association appeared stronger for women “keeping house” or with <12 years education. Exposure in the first trimester was also associated with increased odds of SGA (odds ratio = 1.5 [95% CI = 1.1 to 2.1]) and term SGA (odds ratio = 1.6 [95% CI = 1.2 to 2.3]).

Conclusions: Unexpected economic contraction during early pregnancy may be associated with reduced fetal growth.

Methods: We used data from the 1979 U.S. National Longitudinal Survey of Youth to test associations between measures of adverse childhood experiences with obesity and smoking and used an instrumental variables approach to address potential measurement error of the exposure.

Results: Models demonstrated associations between childhood physical abuse and obesity at age 40 years (OR 1.23, 95% CI 1.00-1.52) and ever smoking (OR 1.83, 95% CI 1.56-2.16), as well as associations between household alcohol abuse (OR 1.53, 95% CI 1.31-1.79) and household mental illness (OR 1.29, 95% CI 1.04-1.60) with ever smoking. We find no evidence of association modification by gender, socioeconomic position or race/ethnicity. Instrumental variables analysis using a sibling's report of adverse childhood experiences demonstrated a relationship between household alcohol abuse and smoking, with a population attributable fraction of 17% (95% CI 2.0% to 37%) for ever smoking and 6.7% (95% CI 1.6% to 12%) for currently smoking.

Conclusions: Findings suggest long-term impacts of childhood exposure to physical abuse, household alcohol abuse and parental mental illness on obesity and smoking, and that the association between household alcohol abuse and smoking is not solely due to measurement error.