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Title: Responding to a 100-Year-Old Challenge from Fisher: A Biometrical Analysis of Adult Height in the NLSY Data Using Only Cousin Pairs
Resulting in 1 citation.
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Rodgers, Joseph Lee Garrison, S. Mason O'Keefe, Patrick Bard, David E. Hunter, Michael D. Beasley, William H. van den Oord, Edwin J. C. G. |
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Responding to a 100-Year-Old Challenge from Fisher: A Biometrical Analysis of Adult Height in the NLSY Data Using Only Cousin Pairs Behavior Genetics 49,5 (September 2019): 444-454. https://link.springer.com/article/10.1007/s10519-019-09967-6 Cohort(s): Children of the NLSY79, NLSY79 Young Adult Publisher: Behavior Genetics Association Keyword(s): Family, Extended; Height; Kinship Permission to reprint the abstract has not been received from the publisher. In 1918, Fisher suggested that his research team had consistently found inflated cousin correlations. He also commented that because a cousin sample with minimal selection bias was not available the cause of the inflation could not be addressed, leaving this inflation as a challenge still to be solved. In the National Longitudinal Survey of Youth (the NLSY79, the NLSY97, and the NLSY-Children/Young Adult datasets), there are thousands of available cousin pairs. Those in the NLSYC/YA are obtained approximately without selection. In this paper, we address Fisher's challenge using these data. Further, we also evaluate the possibility of fitting ACE models using only cousin pairs, including full cousins, half-cousins, and quarter-cousins. To have any chance at success in such a restricted kinship domain requires an available and highly-reliable phenotype; we use adult height in our analysis. Results provide a possible answer to Fisher's challenge, and demonstrate the potential for using cousin pairs in a stand-alone analysis (as well as in combination with other biometrical designs). |
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Bibliography Citation
Rodgers, Joseph Lee, S. Mason Garrison, Patrick O'Keefe, David E. Bard, Michael D. Hunter, William H. Beasley and Edwin J. C. G. van den Oord. "Responding to a 100-Year-Old Challenge from Fisher: A Biometrical Analysis of Adult Height in the NLSY Data Using Only Cousin Pairs." Behavior Genetics 49,5 (September 2019): 444-454. https://link.springer.com/article/10.1007/s10519-019-09967-6.
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