Search Results

Source: American Journal of Obstetrics and Gynecology
Resulting in 2 citations.
1. Ding, Wenqin
Xu, Yuxiang
Kondracki, Anthony J.
Sun, Ying
Childhood Adversity and Accelerated Reproductive Events: A Systematic Review and Meta-Analysis
American Journal of Obstetrics and Gynecology published online (10 October 2023).
Also: https://doi.org/10.1016/j.ajog.2023.10.005
Cohort(s): NLSY79
Publisher: Elsevier
Keyword(s): Abuse, Sexual/Physical/Emotional; Adverse Childhood Experiences (ACEs); Birth Outcomes; Births; Births, Premature/Preterm; Childbearing, Adolescent; Childhood; Childhood Adversity/Trauma; Family Characteristics; Family Dynamics; Life History Theory; Life Outcomes; Menarche/First Menstruation; Meta-analysis; Miscarriage/Pregnancy Loss; Pregnancy and Pregnancy Outcomes; Pregnancy, Adolescent; Puberty; Reproductive Events; Sexual Activity; Sexual Reproduction; Socioeconomic Background; Socioeconomic Factors; Socioeconomic Status (SES)

Objective: Accelerated female reproductive events represent the early onset of reproductive events involving puberty, menarche, pregnancy loss, first sexual intercourse, first birth, parity, and menopause. This study aimed to explore the association between childhood adversity and accelerated female reproductive events.

Data Sources: PubMed, Web of Science, and Embase were systematically searched from September 22, 2022 to September 23, 2022.

Study Eligibility Criteria: Observational cohort, cross-sectional, and case–control studies in human populations were included if they reported the time of reproductive events for female individuals with experience of childhood adversity and were published in English.

Methods: Two reviewers independently screened studies, obtained data, and assessed study quality, and conflicts were resolved by a third reviewer. Dichotomous outcomes were evaluated using meta-analysis, and pooled odds ratios and 95% confidence intervals were generated using random-effects models. Moderation analysis and meta-regression were used to investigate heterogeneity.

Results: In total, 21 cohort studies, 9 cross-sectional studies, and 3 case–control studies were identified. Overall, female individuals with childhood adversity were nearly 2 times more likely to report accelerated reproductive events than those with no adversity exposure (odds ratio, 1.91; 95% confidence interval, 1.33–2.76; I2=99.6%; P<.001). Moderation analysis indicated that effect sizes for the types of childhood adversity ranged from an odds ratio of 1.61 (95% confidence interval, 1.23–2.09) for low socioeconomic status to 2.13 (95% confidence interval, 1.14–3.99) for dysfunctional family dynamics. Among the 7 groups based on different reproductive events, including early onset of puberty, early menarche, early sexual initiation, teenage childbirth, preterm birth, pregnancy loss, and early menopause, early sexual initiation had a nonsignifican t correlation with childhood adversity (odds ratio, 2.70; 95% confidence interval, 0.88–8.30; I2=99.9%; P<.001). Considerable heterogeneity (I2>75%) between estimates was observed for over half of the outcomes. Age, study type, and method of data collection could explain 35.9% of the variance.

Conclusion: The literature tentatively corroborates that female individuals who reported adverse events in childhood are more likely to experience accelerated reproductive events. This association is especially strong for exposure to abuse and dysfunctional family dynamics. However, the heterogeneity among studies was high, requiring caution in interpreting the findings and highlighting the need for further evaluation of the types and timing of childhood events that influence accelerated female reproductive events.

Bibliography Citation
Ding, Wenqin, Yuxiang Xu, Anthony J. Kondracki and Ying Sun. "Childhood Adversity and Accelerated Reproductive Events: A Systematic Review and Meta-Analysis." American Journal of Obstetrics and Gynecology published online (10 October 2023).
2. Margerison-Zilko, Claire E.
Rehkopf, David
Abrams, Barbara
Association of Maternal Gestational Weight Gain with Short- and Long-term Maternal and Child Health Outcomes
American Journal of Obstetrics and Gynecology 202,6 (June 2010): 574.e1-574.e8.
Also: http://www.ncbi.nlm.nih.gov/pubmed/20132923
Cohort(s): Children of the NLSY79, NLSY79
Publisher: Elsevier
Keyword(s): Birth Outcomes; Birthweight; Body Mass Index (BMI); Child Growth; Child Health; Mothers, Health; Obesity; Pre/post Natal Behavior; Weight

OBJECTIVE: The purpose of this study was to investigate the associations between gestational weight gain (GWG) and small- and large-for-gestational-age (SGA, LGA), cesarean delivery, child overweight, and maternal postpartum weight retention in a diverse sample of women in the Unites States.

STUDY DESIGN: We estimated associations between GWG (continuous and within categories defined by the Institute of Medicine), maternal prepregnancy body mass index, and each outcome in 4496 births in the National Longitudinal Survey of Youth 1979, which was a prospective cohort.

RESULTS: GWG (kilograms) was associated with decreased risk of SGA and increased risk of LGA, cesarean delivery, postpartum weight retention, and child overweight independent of maternal demographic and pregnancy characteristics. Gain above the Institute of Medicine guidelines was associated with decreased risk of SGA and increased risk of all other outcomes.

CONCLUSION: Excessive gain may have long-term consequences for maternal and child body size, but the benefits of lower gain must be balanced against risk of SGA. Copyright © 2010 Mosby, Inc. All rights reserved.

Bibliography Citation
Margerison-Zilko, Claire E., David Rehkopf and Barbara Abrams. "Association of Maternal Gestational Weight Gain with Short- and Long-term Maternal and Child Health Outcomes." American Journal of Obstetrics and Gynecology 202,6 (June 2010): 574.e1-574.e8.